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| Pal M, Krajnc I, Potočnik U Med Mes 2008; 4:88-93 |
Osteoartritis: patogeneza in farmakološko zdravljenje
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Osteoarthritis: the pathogenesis and pharmacological therapyOsteoarthritis is a progressive disorder characterized by destruction of articular cartilage and subchondral bone and by synovial changes. Alleviation of pain and inhibition of inflammation are the primary goals of pharmacotherapy of osteoarthritis (OA). Disease modifying therapy is under development. Current knowledge about pathogenesis of OA reveals new pharmacological targets. |
Ključne besede:sklepni hrustanec, kost, nove farmakološke tarče, analgetiki, učinkovine z vplivom na potek osteoartritisa (DMOAD) |
Key words:articular cartilage, bone, new pharmacological targets, analgetics, disease-modifying OA drugs (DMOAD) |
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